Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 08/04/22 20:00 | 08/04/22 20:00 | FC Lorient | AS St. Etienne | 6-2 | 2 - 5 points |
| 09/04/22 16:00 | 09/04/22 16:00 | Stade Reims | Stade Rennes | 2-3 | 2 - 5 points |
| 09/04/22 20:00 | 09/04/22 20:00 | Clermont Foot | Paris St. Germain | 1-6 | 2 - 5 points |
| 10/04/22 12:00 | 10/04/22 12:00 | Girondins Bordeaux | FC Metz | 3-1 | 2 - 5 points |
| 10/04/22 14:00 | 10/04/22 14:00 | SCO Angers | OSC Lille | 1-1 | 2 - 5 points |
| 10/04/22 14:00 | 10/04/22 14:00 | Stade Brest 29 | FC Nantes | 1-1 | 2 - 5 points |
| 10/04/22 14:00 | 10/04/22 14:00 | AS Monaco | ES Troyes AC | 2-1 | 2 - 5 points |
| 10/04/22 16:05 | 10/04/22 16:05 | RC Lens | OGC Nice | 3-0 | 2 - 5 points |
| 10/04/22 18:00 | 10/04/22 18:00 | Racing Club Strasbourg | Olympique Lyon | 1-1 | 2 - 5 points |
| 10/04/22 20:00 | 10/04/22 20:00 | Olympique Marseille | HSC Montpellier | 2-0 | 2 - 5 points |