Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 02/04/22 16:00 | 02/04/22 16:00 | OGC Nice | Stade Rennes | 1-1 | 2 - 5 points |
| 02/04/22 18:00 | 02/04/22 18:00 | OSC Lille | Girondins Bordeaux | 0-0 | 2 - 5 points |
| 03/04/22 12:00 | 03/04/22 12:00 | Racing Club Strasbourg | RC Lens | 1-0 | 2 - 5 points |
| 03/04/22 14:00 | 03/04/22 14:00 | HSC Montpellier | Stade Brest 29 | 1-2 | 2 - 5 points |
| 03/04/22 14:00 | 03/04/22 14:00 | AS St. Etienne | Olympique Marseille | 2-4 | 2 - 5 points |
| 03/04/22 14:00 | 03/04/22 14:00 | ES Troyes AC | Stade Reims | 1-0 | 2 - 5 points |
| 03/04/22 14:00 | 03/04/22 14:00 | Clermont Foot | FC Nantes | 2-3 | 2 - 5 points |
| 03/04/22 14:00 | 03/04/22 14:00 | FC Metz | AS Monaco | 1-2 | 2 - 5 points |
| 03/04/22 16:05 | 03/04/22 16:05 | Olympique Lyon | SCO Angers | 3-2 | 2 - 5 points |
| 03/04/22 19:45 | 03/04/22 19:45 | Paris St. Germain | FC Lorient | 5-1 | 2 - 5 points |