Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 18/02/22 20:00 | 18/02/22 20:00 | OSC Lille | FC Metz | 0-0 | 2 - 5 points |
| 19/02/22 16:00 | 19/02/22 16:00 | RC Lens | Olympique Lyon | 1-1 | 2 - 5 points |
| 19/02/22 20:00 | 19/02/22 20:00 | FC Nantes | Paris St. Germain | 3-1 | 2 - 5 points |
| 20/02/22 12:00 | 20/02/22 12:00 | OGC Nice | SCO Angers | 1-0 | 2 - 5 points |
| 20/02/22 14:00 | 20/02/22 14:00 | FC Lorient | HSC Montpellier | 0-1 | 2 - 5 points |
| 20/02/22 14:00 | 20/02/22 14:00 | Stade Reims | Stade Brest 29 | 1-1 | 2 - 5 points |
| 20/02/22 14:00 | 20/02/22 14:00 | Stade Rennes | ES Troyes AC | 4-1 | 2 - 5 points |
| 20/02/22 14:00 | 20/02/22 14:00 | AS St. Etienne | Racing Club Strasbourg | 2-2 | 2 - 5 points |
| 20/02/22 16:05 | 20/02/22 16:05 | Girondins Bordeaux | AS Monaco | 1-1 | 2 - 5 points |
| 20/02/22 19:45 | 20/02/22 19:45 | Olympique Marseille | Clermont Foot | 0-2 | 2 - 5 points |