Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 05/11/21 20:00 | 05/11/21 20:00 | RC Lens | ES Troyes AC | 4-0 | 2 - 5 points |
| 06/11/21 16:00 | 06/11/21 16:00 | OSC Lille | SCO Angers | 1-1 | 2 - 5 points |
| 06/11/21 20:00 | 06/11/21 20:00 | Girondins Bordeaux | Paris St. Germain | 2-3 | 2 - 5 points |
| 07/11/21 12:00 | 07/11/21 12:00 | Olympique Marseille | FC Metz | 0-0 | 2 - 5 points |
| 07/11/21 14:00 | 07/11/21 14:00 | FC Lorient | Stade Brest 29 | 1-2 | 2 - 5 points |
| 07/11/21 14:00 | 07/11/21 14:00 | FC Nantes | Racing Club Strasbourg | 2-2 | 2 - 5 points |
| 07/11/21 14:00 | 07/11/21 14:00 | Stade Reims | AS Monaco | 0-0 | 2 - 5 points |
| 07/11/21 14:00 | 07/11/21 14:00 | AS St. Etienne | Clermont Foot | 3-2 | 2 - 5 points |
| 07/11/21 16:05 | 07/11/21 16:05 | OGC Nice | HSC Montpellier | 0-1 | 2 - 5 points |
| 07/11/21 19:45 | 07/11/21 19:45 | Stade Rennes | Olympique Lyon | 4-1 | 2 - 5 points |