Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 15/10/21 20:00 | 15/10/21 20:00 | Paris St. Germain | SCO Angers | 2-1 | 2 - 5 points |
| 16/10/21 16:00 | 16/10/21 16:00 | Clermont Foot | OSC Lille | 1-0 | 2 - 5 points |
| 16/10/21 20:00 | 16/10/21 20:00 | Olympique Lyon | AS Monaco | 2-0 | 2 - 5 points |
| 17/10/21 12:00 | 17/10/21 12:00 | ES Troyes AC | OGC Nice | 1-0 | 2 - 5 points |
| 17/10/21 14:00 | 17/10/21 14:00 | Racing Club Strasbourg | AS St. Etienne | 5-1 | 2 - 5 points |
| 17/10/21 14:00 | 17/10/21 14:00 | Girondins Bordeaux | FC Nantes | 1-1 | 2 - 5 points |
| 17/10/21 14:00 | 17/10/21 14:00 | Stade Brest 29 | Stade Reims | 1-1 | 2 - 5 points |
| 17/10/21 14:00 | 17/10/21 14:00 | FC Metz | Stade Rennes | 0-3 | 2 - 5 points |
| 17/10/21 16:05 | 17/10/21 16:05 | HSC Montpellier | RC Lens | 1-0 | 2 - 5 points |
| 17/10/21 19:45 | 17/10/21 19:45 | Olympique Marseille | FC Lorient | 4-1 | 2 - 5 points |