Schedule
| Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|
| 26/08/22 17:30 | 26/08/22 17:25 | Fortuna Düsseldorf | Jahn Regensburg | 4-0 | 1 - 3 points |
| 26/08/22 17:30 | 26/08/22 17:25 | Arminia Bielefeld | Eintracht Braunschweig | 4-1 | 1 - 3 points |
| 27/08/22 12:00 | 27/08/22 11:55 | SV Darmstadt 98 | 1. FC Heidenheim 1846 | 2-2 | 1 - 3 points |
| 27/08/22 12:00 | 27/08/22 11:55 | FC St. Pauli | SC Paderborn 07 | 2-2 | 1 - 3 points |
| 27/08/22 12:00 | 27/08/22 11:55 | Karlsruher SC | FC Hansa Rostock | 2-0 | 1 - 3 points |
| 27/08/22 19:30 | 27/08/22 19:25 | 1. FC Nürnberg | Hamburger SV | 0-2 | 1 - 3 points |
| 28/08/22 12:30 | 28/08/22 12:25 | Holstein Kiel | SV Sandhausen | 1-0 | 1 - 3 points |
| 28/08/22 12:30 | 28/08/22 12:25 | 1. FC Kaiserslautern | 1. FC Magdeburg | 4-4 | 1 - 3 points |
| 28/08/22 12:30 | 28/08/22 12:25 | Hannover 96 | SpVgg Greuther Fürth | 2-1 | 1 - 3 points |