| Date | Home | Away | Result |
|---|---|---|---|
| 12/09/25 19:30 | Bayer 04 Leverkusen | Eintracht Frankfurt | 3-1 |
| 13/09/25 14:30 | 1. FC Union Berlin | 1899 Hoffenheim | 2-4 |
| 13/09/25 14:30 | VfL Wolfsburg | 1. FC Köln | 3-3 |
| 13/09/25 14:30 | 1. FC Heidenheim 1846 | Borussia Dortmund | 0-2 |
| 13/09/25 14:30 | SC Freiburg | VfB Stuttgart | 3-1 |
| 13/09/25 14:30 | FSV Mainz 05 | RB Leipzig | 0-1 |
| 13/09/25 17:30 | FC Bayern Munich | Hamburger SV | 5-0 |
| 14/09/25 14:30 | FC St. Pauli | FC Augsburg | 2-1 |
| 14/09/25 16:30 | Bor. Mönchengladbach | Werder Bremen | 0-4 |