| Date | Home | Away | Result |
|---|---|---|---|
| 03/02/25 17:00 | Gazisehir Gaziantep FK | Galatasaray Istanbul | 0-1 |
| 03/02/25 19:45 | Cagliari Calcio | Lazio Rom | 1-2 |
| 03/02/25 20:00 | Chelsea FC | West Ham United | 2-1 |
| 03/02/25 20:00 | Middlesbrough FC | AFC Sunderland | 2-3 |
| 03/02/25 20:00 | Defensa y Justicia Florencio Varela | Central Cordoba | 2-1 |