Schedule
| Competition | Date | Dead line | Home | Away | Result | Points rule |
|---|---|---|---|---|---|---|
| FB | 24/08/21 20:00 | 24/08/21 20:00 | (NED) PSV Eindhoven | (POR) Benfica Lissabon | 0-0 | 3 - 5 points |
| FB | 24/08/21 20:00 | 24/08/21 20:00 | (HUN) Ferencváros Budapest | (SUI) Young Boys Bern | 2-3 | 3 - 5 points |
| FB | 24/08/21 20:00 | 24/08/21 20:00 | (BUL) Ludogorez Rasgrad | (SWE) Malmö FF | 2-1 | 3 - 5 points |
| FB | 25/08/21 20:00 | 25/08/21 20:00 | (DEN) IF Brøndby | (AUT) RB Salzburg | 1-2 | 3 - 5 points |
| FB | 25/08/21 20:00 | 25/08/21 20:00 | (UKR) Schachtar Donezk | (FRA) AS Monaco | 2-2a.e.t | 3 - 5 points |
| FB | 25/08/21 20:00 | 25/08/21 20:00 | (KRO) Dinamo Zagreb | (MDA) Sheriff Tiraspol | 0-0 | 3 - 5 points |